These neurons are the final output neurons of the vertebrate retina. They collect visual information from bipolar cells and amacrine cells and transmit it to the brain via the optic nerve. This process is fundamental to visual perception, converting graded potentials from preceding retinal cells into action potentials capable of traveling long distances.
The significance of these retinal neurons lies in their role as the bridge between the eye and the brain. They are responsible for processing and relaying information about form, color, movement, and depth. Historically, understanding their function has been crucial in unraveling the complexities of how the visual system encodes and transmits information, leading to advancements in understanding visual impairments and developing potential treatments.